St. Jude Children's Research Hospital
Memphis, TN, USA
A postdoctoral fellowship is available in the laboratory of Dr. Jonathan Yen in the Division of Experimental Hematology. Project Description: We are seeking a highly motivated and talented Postdoctoral Research Fellow to join our cutting-edge research team focused on developing lipid nanoparticle (LNP)-based therapeutic strategies for targeting hematopoietic stem cells (HSCs). The successful candidate will work in a collaborative and interdisciplinary environment to advance novel genome editor delivery technologies and improve therapeutic outcomes in hematological disorders. Position Responsibilities: LNP Design and Characterization Design, synthesize, and characterize LNP formulations optimized for targeting HSCs. Optimize lipid composition, particle size, and surface modifications (e.g., antibody conjugation for HSC targeting). Perform dynamic light scattering (DLS), zeta potential, and RiboGreen RNA concentration analyses to characterize nanoparticles....