15 jobs found in Memphis, TN

Location Memphis, TN Category Postdoc Department Cell and Molecular Biology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7632 Job Description The Gibson and Skiniotis research groups invite applications for a Postdoctoral Research Associate to lead a joint effort to uncover fundamental mechanisms of higher-order genome organization. We seek an ambitious postdoctoral scholar that will use cryo-electron microscopy and tomography (cryo-EM/cryo-ET) to analyze chromatin structures within both cells and condensed chromatin assemblies produced in vitro. Candidates will benefit from two world-class training environments and learn modern concepts and techniques in both chromatin biochemistry and biophysics as well as structural analyses using cryogenic electron microscopy. We are seeking a dedicated scientist with a track record of success and a thoughtful and collaborative mindset to drive high-impact...

Location Memphis, TN Department Developmental Neurobiology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7797 Job Description Are you passionate about translating groundbreaking science into compelling stories that inform, inspire, and drive impact? The Science Research Writer (SRW) for the Department of Developmental Neurobiology serves as a Science Communications Specialist. The SRW reports directly to the Administrative Director, also part of that team. The SRW shares with mainly with internal audiences how DNB contributes to St. Jude's mission to find cures and save lives in ways that reflect our leadership culture, collaborative values, and scientific impact. This communication may take any form (written articles, marketing materials, videos, infographics, etc.) and may be delivered through a variety of outlets (website, presentations, journal articles, etc.). The SRW also pitches stories and nominates...

Location Memphis, TN Category Postdoc Department Hematology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR6860 Job Description A postdoctoral research associate position is available in the Yamashita lab. Project Description: Hematopoietic stem cells (HSCs) sustain lifelong blood production, and defects in their regulation contribute to diverse hematologic disorders, including clonal hematopoiesis, hematologic malignancies, and aplastic anemia. This project aims to define how T cell-mediated immune surveillance regulates HSC fate in the bone marrow and influences disease outcomes, ranging from immune tolerance and clonal expansion to graft-versus-leukemia activity and bone marrow failure. Using state-of-the-art mouse models, immunologic approaches, and single-cell technologies, the successful candidate will investigate the cellular and molecular mechanisms that govern immune-stem cell...

Location Memphis, TN Category Postdoc Department Oncology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7547 Job Description Postdoctoral Research Associate Position: Dr. Chunliang Li Lab, Division of Molecular Oncology, Department of Oncology. The Li Lab in the Division of Molecular Oncology, Department of Oncology at St. Jude Children's Research Hospital is seeking a highly motivated Postdoctoral Fellow to join our research team. The postdoctoral fellow candidate is expected to have a strong background in molecular biology and great enthusiasm for exploring scientific discovery in cancer biology. The successful candidate will leverage cutting-edge, multidisciplinary research technologies in drug-controlled, degradable, oncogene-induced mouse tumor models to study dysregulated transcription in oncogenesis, tumor maintenance, and metastasis. Position Responsibilities: The postdoctoral fellow...

Location Memphis, TN Category Postdoc Department Host Microbe Interactions Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7601 Job Description A Postdoctoral Research Associate position is available in the laboratory of Dr. Salvador Almagro-Moreno, Associate Member in the Department of Host-Microbe Interactions at St. Jude Children's Research Hospital. The Moreno lab investigates the emergence and evolution of bacterial pathogens. Our major research interests include elucidating the molecular strategies that bacterial pathogens develop for host colonization, virulence regulation and dispersal from the host. Our research program focuses on pathogenic members of the family Vibrionaceae with a strong emphasis on the intestinal pathogen Vibrio cholerae and the climate-sensitive pathogen Vibrio vulnificus, source of fulminant septicemia. Our goal is to gain the knowledge to a) effectively forecast the...

Location Memphis, TN Category Faculty Department Oncology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7722 Job Description SJCRH We seek a highly motivated clinician scientist or clinician educator at the Instructor, Assistant, Associate, or Full Member (Professor) level to join the Division of Cancer Survivorship within the Department of Oncology at St. Jude Children's Research Hospital. The candidate should have an MD, MD/PhD, or DO degree and Board certified or Board eligible in family medicine, pediatrics, internal medicine, or pediatric hematology-oncology with a track record of excellence in academic potential, a strong interest in cancer survivorship research, and a commitment to outstanding clinical care for survivors of childhood and adolescent cancer. The position will report to the Director of the Division of Survivorship and provide clinical care in the After Completion of Therapy...

Location Memphis, TN Category Postdoc Department Developmental Neurobiology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7470 Job Description A postdoctoral research associate position is available with Dr. Bikoff. The Bikoff lab (https://www.stjude.org/research/labs/bikoff-lab.html) in the Department of Developmental Neurobiology at St. Jude Children's Research Hospital is seeking a Postdoctoral Research Associate interested in studying motor circuitry in mice. Projects will focus on the synaptic and circuit organization of neurons in the spinal cord, and how these circuits ultimately shape motor output. Our laboratory aims to understand the organization and function of neural circuits that control movement, with a particular focus on circuits in the spinal cord that directly control motor output. Projects in the lab can be broadly organized into three thematic areas: dissecting the diversity...

Location Memphis, TN Category Postdoc Department Bone Marrow Transplant and Cellular Therapy Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7783 Job Description A postdoctoral research associate position is available in the lab of Dr. Senthil Bhoopalan. Project Description: Bone marrow failure (BMF) disorders are catastrophic diseases of childhood that result in failure to produce hematopoietic cells leading to severe morbidity and eventually mortality. Treatment options are limited to supportive care and allogeneic bone marrow transplantation. We are interested in developing curative therapies for patients with these rare but severe disorders. Using a combination of disease model systems such as induced pluripotent stem cell-derived hematopoietic stem cells and engineered hematopoietic stem cells from healthy donors to model patient mutations, we have advanced development of gene therapy for...

Location Memphis, TN Category Postdoc Department Cell and Molecular Biology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7461 Job Description The Opferman Laboratory at St. Jude Children's Research Hospital is seeking a highly motivated and creative Postdoctoral Fellow to how mitochondrial biology and the BCL-2 family protein MCL-1 govern normal hematopoiesis, stem cell maintenance, lineage commitment, and cellular stress responses, and how these pathways become dysregulated in acute myeloid leukemia (AML) and other hematologic malignancies. Our laboratory integrates molecular and cellular biology, mouse genetics, biochemistry, cancer biology, metabolism, epigenetics, genomics, proteomics, and advanced imaging to address fundamental questions in stem cell and cancer biology. Current projects explore the non-apoptotic functions of MCL-1, mitochondrial metabolism and quality control, mechanisms...

Location Memphis, TN Category Laboratory Sciences & Support Department Hematology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7154 Job Description The Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results. At St. Jude Children's Research Hospital, talented faculty and staff work together and with colleagues worldwide to advance the research and treatment of pediatric cancer and other catastrophic diseases. We are seeking an outstanding, highly motivated, and creative Scientist to join Dr. Jonathan Yen's lab and the Therapeutic Genome Engineering (TGEn) group. You will be part of a multidisciplinary team of scientists and clinical researchers helping to...

Location Memphis, TN Category Laboratory Sciences & Support Department Hematology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7689 Job Description A Lead or Senior Scientist opportunity with the Tsai Lab to develop a therapeutic platform for in vivo base editing treatments and drug products to treat patients with bone marrow failure disorders at St. Jude. Help us build an individualized therapeutic base editing platform to treat St. Jude patients with rare bone marrow failure disorders by correcting their disease-causing mutations in their hematopoietic stem cells in vivo. Dr. Tsai leads the recently launched DRIVE project (Delivering Rare-disease In vivo Editors), funding a multi-institutional, public-private partnership to develop in vivo base editors for treatment of bone marrow failure disorders. Bring your expertise in genome editing drug development to a Lead Scientist role in the Tsai...

Location Memphis, TN Category Laboratory Sciences & Support Department Computational Biology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7826 Job Description The laboratory of Dr. Paul Geeleher (appointments in the Comprehensive Cancer Center, the Graduate School of Biomedical Science, and the Department of Computational Biology) is seeking a wet-lab Researcher or Senior Researcher to support work on mechanistic dissection of hits from high throughput drug and CRISPR screens, the development of new drug combinations, and mechanistic dissection of drug resistance mechanisms in neuroblastoma. Job Description: Dr. Geeleher's laboratory tightly integrates wet-bench and computational approaches, aimed at improving outcomes in pediatric cancers, especially neuroblastoma. Our group has spearheaded publications in e.g. Nature, Genome Biology, Journal of the National Cancer Institute (JNCI), and...

Location Memphis, TN Category Postdoc Department Computational Biology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7387 Job Description A postdoctoral research associate position is available in the Geeleher lab. The Geeleher Lab tightly integrates computational/AI-based analysis of high-throughput genomics datasets (e.g. single-cell / spatial genomics, functional screens) with wet-bench experimental work. We ultimately aim to improve outcomes for children with cancer, with a particular focus on neuroblastoma and other high-risk pediatric solid tumors. Our hybrid wet-dry lab has led publications in journals including Nature, Genome Biology, the Journal of the National Cancer Institute, and Nature Communications, and is supported by NIH funding, including R01 (NCI renewal recently scored 1st percentile) and R35 awards, as well as institutional funding from ALSAC. We are seeking a dry-lab...

Location Memphis, TN Category Postdoc Department Hematology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7523 Job Description A postdoctoral research associate position is available in the Weiss lab. Healthy individuals produce billions of red blood cells each day in a process called "erythropoiesis". The postdoctoral fellow will study the physiology and gene regulation of erythropoiesis using a number of different model systems, including tissue culture cells, mouse models and blood forming cells from deidentified human subjects. Understanding erythropoiesis better will allow us to develop new cures for common blood diseases that affect many individuals across the world. Position Responsibilities: 1. Analyze gene expression during erythropoiesis through molecular biology and informatics. 2. Develop new cellular models for human blood disorder including sickle cell disease. 3. Study roles for...

Location Memphis, TN Category Postdoc Department Host Microbe Interactions Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR7809 Job Description A Postdoctoral Research Associate position is available in the Kumar Laboratory within the Department of Host-Microbe Interactions at St. Jude Children's Research Hospital. The Kumar Lab investigates how xenobiotics (medications, dietary compounds) and host immune factors remodel the gut microbiome to alter intestinal homeostasis. We integrate clinical and high-throughput omics datasets with mechanistic molecular microbiology, anaerobic culturomics, and gnotobiotic animal models to dissect how microbiome alterations govern susceptibility to infectious and non-infectious gastrointestinal diseases. See our recent publication: Kumar et al. Nature, 644, 506-515 (2025) Position Responsibilities: We are seeking an ambitious, highly motivated Postdoctoral...