St. Jude Children's Research Hospital
Memphis, TN
Location Memphis, TN Category Postdoc Department Hematology Shift Weekday Day Position Type Full Time Scheduled Weekly Hours 40 Req # JR6860 Job Description A postdoctoral research associate position is available in the Yamashita lab. Project Description: Hematopoietic stem cells (HSCs) sustain lifelong blood production, and defects in their regulation contribute to diverse hematologic disorders, including clonal hematopoiesis, hematologic malignancies, and aplastic anemia. This project aims to define how T cell-mediated immune surveillance regulates HSC fate in the bone marrow and influences disease outcomes, ranging from immune tolerance and clonal expansion to graft-versus-leukemia activity and bone marrow failure. Using state-of-the-art mouse models, immunologic approaches, and single-cell technologies, the successful candidate will investigate the cellular and molecular mechanisms that govern immune-stem cell...