Pharmacia & Upjohn Company
San Diego, CA, USA
The successful candidate will join the Translational Modeling and Simulation (TMS) team within Pfizer’s Department of Pharmacokinetics, Dynamics, and Metabolism (PDM). As a core member of multidisciplinary project teams, the candidate will leverage principles and practices of quantitative translational pharmacology (PKPD, PBPK, QSP) to influence decision making from project ideation through early clinical development for both biologic and small molecule modalities. Emphasis will be in oncology with a particular focus on biologics but expand to small molecule project support and opportunities in other therapeutic areas such as immunology and inflammation, metabolic diseases, and infectious diseases. Responsibilities: Work closely with multidisciplinary project teams to develop and implement mechanistic mathematical models of pharmacology to aid in target selection, target prioritization, therapeutic modality selection, chemical/biotherapeutic optimization, quantification of...